The meaning ofLOSEis to miss from one's possession or from a customary or supposed place. How to uselosein a sentence.
loseverb (NO LONGER POSSESS) [ T ] to no longer have something, because it has been taken away from you, either by accident or purposely:
2. to fail to keep or maintain: toloseone's balance. 3. to suffer thelossor deprivation of: tolosea parent.

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Definition ofloseverb in Oxford Advanced American Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.
The verb tolosemeans something has gone missing. Maybe it's your car keys. Maybe it's points in a game. Maybe it's the love of your life. Sorry about that. You can physicallylosesomething by misplacing it, or you canloseyour pride in a competition.
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lose(lo̅o̅z), v., lost, los•ing. v.t. to come to be without (something in one's possession or care), through accident, theft, etc., so that there is little or no prospect of recovery: I'm sure I've merely misplaced my hat, notlostit.
LOSE definition:to come to be without(something in one's possession or care), through accident, theft, etc., so that there is little or no prospect of recovery. See examples of lose used in a sentence.

Losedefinition: To be unsuccessful in retaining possession of; mislay.